Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.68 |
| ▸ | ITGAV | P06756 | 16/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7401107 | 0.99 | ITGB3 (0.67) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7400967 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL7405506 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7404187 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL8552051 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL7982685 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL8547542 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Hydrochloric Acid SCHEMBL8552522 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7402263 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7410391 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |