Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399259 | 0.85 | F2 (0.60) | F10F2PRSS1PLGPLAU | |
| SCHEMBL7406430 | 0.81 | F10 (0.76) | F10F2PRSS1PLGPLAU | |
| SCHEMBL6988665 | 0.80 | MTOR (0.47) | F10F2PRSS1PLGPLAU | |
| SCHEMBL10318990 | 0.74 | CYP3A4 (0.63) | KDM4ENPC1TP53PKMRAB9A | |
| Hydrochloric Acid SCHEMBL29202497 | 0.73 | F2 (0.68) | F10F2PRSS1PLGPLAU | |
| SCHEMBL6680675 | 0.73 | F2 (0.51) | F10F2PRSS1PLGPLAU | |
| SCHEMBL548406 | 0.73 | F2 (0.58) | F10F2PRSS1PLGPLAU | |
| SCHEMBL5237850 | 0.72 | F10 (0.51) | F10F2PRSS1PLGPLAU | |
| SCHEMBL16053859 | 0.71 | MTOR (0.43) | KDM4ENPC1TP53PKMRAB9A | |
| Water SCHEMBL4316286 | 0.71 | F10 (0.44) | F10F2PRSS1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |