Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.60 |
| ▸ | F10 | P00742 | 4/20 | 0.60 |
| ▸ | F7 | P08709 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410845 | 0.85 | F10 (0.51) | F2F10F7NPC1RAB9A | |
| SCHEMBL23793907 | 0.84 | F2 (0.83) | F2F10F7KLK1KLK5 | |
| SCHEMBL7479169 | 0.81 | F10 (0.71) | F2F10F7KLK1KLK5 | |
| SCHEMBL6163820 | 0.81 | F10 (0.85) | F2F10F7KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL28579078 | 0.80 | F10 (0.82) | F2F10F7KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL30386514 | 0.80 | F10 (0.82) | F2F10F7KLK1KLK5 | |
| SCHEMBL7409416 | 0.80 | F10 (0.59) | F2F10F7KLK1KLK5 | |
| SCHEMBL7408229 | 0.80 | F2 (0.59) | F2F10F7KLK1KLK5 | |
| SCHEMBL7403000 | 0.78 | F10 (0.58) | F2F10F7KLK1KLK5 | |
| SCHEMBL28050241 | 0.78 | RAB9A (0.68) | CYP3A4MEN1KMT2AGAAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |