Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.70 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414713 | 0.98 | ESR1 (0.73) | ESR1ESR2F2 | |
| SCHEMBL6174326 | 0.85 | ESR1 (0.77) | ESR1ESR2F2 | |
| SCHEMBL7768296 | 0.84 | ESR1 (0.71) | ESR1ESR2F2 | |
| SCHEMBL4651940 | 0.84 | ESR1 (0.98) | ESR1ESR2F2 | |
| SCHEMBL7409821 | 0.84 | ESR1 (0.98) | ESR1ESR2F2 | |
| Oxalic Acid SCHEMBL7983157 | 0.84 | ESR1 (0.64) | ESR1ESR2F2 | |
| Oxalic Acid SCHEMBL7773946 | 0.83 | ESR1 (0.82) | ESR1ESR2F2 | |
| SCHEMBL6595006 | 0.83 | ESR1 (1.00) | ESR1ESR2F2 | |
| SCHEMBL4650742 | 0.83 | ESR1 (1.00) | ESR1ESR2F2 | |
| SCHEMBL6595547 | 0.83 | ESR1 (0.92) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |