Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.33 |
| ▸ | PLG | P00747 | 3/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414004 | 0.91 | F10 (0.34) | F10F2PRSS1PLGPROC | |
| SCHEMBL7414989 | 0.85 | F10 (0.46) | F10F2PRSS1PLGPROC | |
| SCHEMBL7412407 | 0.83 | F10 (0.35) | F10F2PRSS1PLGPROC | |
| SCHEMBL7414194 | 0.83 | CACNA1S (0.31) | F10PRSS1PLG | |
| SCHEMBL7126537 | 0.83 | F10 (0.49) | F10F2PRSS1PLGPROC | |
| SCHEMBL7414537 | 0.82 | CACNA1S (0.31) | — | |
| SCHEMBL7408430 | 0.82 | F10 (0.48) | F10F2PRSS1PLGPROC | |
| SCHEMBL7408558 | 0.82 | F10 (0.48) | F10F2PRSS1PLGPROC | |
| SCHEMBL7412543 | 0.82 | F10 (0.36) | F10F2PRSS1PLGPROC | |
| SCHEMBL7408226 | 0.81 | F10 (0.47) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | claimed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | claimed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |