Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.35 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | PLG | P00747 | 4/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411813 | 0.86 | F10 (0.36) | F10F2PRSS1PLGPROC | |
| SCHEMBL7408558 | 0.85 | F10 (0.48) | F10F2PRSS1PLGPROC | |
| SCHEMBL7412543 | 0.85 | F10 (0.36) | F10F2PRSS1PLGPROC | |
| SCHEMBL7408430 | 0.85 | F10 (0.48) | F10F2PRSS1PLGPROC | |
| SCHEMBL7417433 | 0.85 | F10 (0.49) | F10F2PRSS1PLGPROC | |
| SCHEMBL7414004 | 0.84 | F10 (0.34) | F10F2PRSS1PLGPROC | |
| SCHEMBL7408226 | 0.84 | F10 (0.47) | F10F2PRSS1PLGPROC | |
| SCHEMBL7411273 | 0.83 | F10 (0.33) | F10F2PRSS1PLGPROC | |
| SCHEMBL7120036 | 0.81 | F10 (0.53) | F10F2PRSS1PLGPROC | |
| SCHEMBL7407496 | 0.81 | F10 (0.39) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054858-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-11-29 | — | — | EP | claimed |
| WO-1999042436-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1999-08-26 | — | — | WO | claimed |