⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372348 | 1.00 | — | — | |
| SCHEMBL8645053 | 0.81 | — | — | |
| SCHEMBL13545070 | 0.81 | — | — | |
| SCHEMBL9397218 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL9397223 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL9200566 | 0.77 | — | — | |
| SCHEMBL9200562 | 0.77 | — | — | |
| SCHEMBL10488288 | 0.74 | — | — | |
| SCHEMBL2069159 | 0.74 | — | — | |
| SCHEMBL10488285 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138350-B2 | N′-cyano-N-halogenalkylimidamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100048646-A1 | N'-Cyano-N-Halogenalkylimidamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20070225374-A1 | Hydroxypropyl Amides for the Treatment of Alzheimer's Disease | ELAN PHARMACEUTICALS, INC. (US) | 2007-09-27 | — | — | US | disclosed |
| US-7262208-B2 | Hydroxypropyl amides for the treatment of Alzheimer's disease | ELAN PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1694635-A2 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER&rsquo;S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005042472-A2 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040039034-A1 | Hydroxypropyl amides for the treatment of Alzheimer's disease | PHARMACIA & UPJOHN COMPANY | 2004-02-26 | — | — | US | disclosed |
| US-6297242-B1 | ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS, VANCOMYCIN-RESISTANT ENTEROCOCCI AND PENICILLIN- AND CEPHALOSPORIN-RESISTANT STREPTOCOCCUS PNEUMONIAE. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-02 | — | — | US | disclosed |
| EP-0643709-A1 | 4-(1-$i(H)-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5276048-A | 4-(1H-pyrrol-1-yl)imidazoles with angiotensin II antagonist activity | WARNER-LAMBERT COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| WO-1993000341-A1 | 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |