Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.76 |
| ▸ | CTSS | P25774 | 5/20 | 0.76 |
| ▸ | CTSL | P07711 | 3/20 | 0.76 |
| ▸ | CTSB | P07858 | 1/20 | 0.76 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.66 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361534 | 1.00 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7402633 | 1.00 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8583863 | 0.95 | CTSK (0.70) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8583860 | 0.93 | CTSK (0.67) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL9617949 | 0.93 | CAPN1 (0.68) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934709 | 0.93 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL9788524 | 0.91 | CTSK (0.71) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL24115146 | 0.90 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL20669315 | 0.90 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL4669748 | 0.90 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786462-B1 | DC107 derivatives | KYOWA HAKKO KOGYO KK (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1200457-A2 | CYSTEINE PROTEASE INHIBITORS | Naeja Pharmaceutical Inc. (CA) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009169-A2 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2001-02-08 | — | — | WO | disclosed |
| US-5733924-A | BACTERICIDES AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0786462-A1 | DC107 DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0134563-B1 | NOVEL AMINOGLYCOSIDE COMPOUNDS AND THEIR ACID ADDITION SALTS AND PROCESS FOR PRODUCTION THEREOF | KOWA COMPANY, LTD. (JP) | 1988-10-19 | — | — | EP | disclosed |
| US-4647656-A | ANTIBIOTICS | KOWA COMPANY, LTD. (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4596819-A | Antidepressive agents | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| US-4564471-A | N-/BENZYLOXYCARBONYL/ASPARTYLPHENYLALANINE | AJINOMOTO CO., INC. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0134563-A1 | Novel aminoglycoside compounds and their acid addition salts and process for production thereof | KOWA COMPANY, LTD. (JP) | 1985-03-20 | — | — | EP | disclosed |
| US-4174312-A | ACYLATION, HYDROLYSIS, SALT FORMATION, CATALYTIC HYDROGENATION | ABBOTT LABORATORIES (US) | 1979-11-13 | — | — | US | disclosed |
| US-4173564-A | 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A | ABBOTT LABORATORIES (US) | 1979-11-06 | — | — | US | disclosed |
| US-4155902-A | ACYLATION, HYDROGENOLYSIS | ABBOTT LABORATORIES (US) | 1979-05-22 | — | — | US | disclosed |
| US-4154727-A | REACTING A GLYCINAMIDE WITH A HALOACETYL HALIDE | SHIONOGI & CO., LTD. (JP) | 1979-05-15 | — | — | US | disclosed |
| US-4091032-A | ANTIMICROBIAL AGENTS | ABBOTT LABORATORIES (US) | 1978-05-23 | — | — | US | disclosed |
| US-4076703-A | 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE | SHIONOGI & CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4076704-A | 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE | SHIONOGI & CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4076702-A | 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE | SHIONOGI & CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4076705-A | 2-O-CHLOROBENZOYL-4-CHLORO-N-METHYL-N(ALPHA)-GLYCYL-GLYCINANILIDE | SHIONOGI & CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4066684-A | PREPARATION OF PEPTIDES | THE DOW CHEMICAL COMPANY (US) | 1978-01-03 | — | — | US | disclosed |