Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 17/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 16/20 | 0.43 |
| ▸ | F10 | P00742 | 16/20 | 0.43 |
| ▸ | F3 | P13726 | 13/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.43 |
| ▸ | F2 | P00734 | 15/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883227 | 0.85 | F7 (0.46) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL5882875 | 0.84 | F7 (0.44) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL7417393 | 0.83 | F7 (0.49) | F7PRSS1F10F3PRSS2 | |
| Hydrochloric Acid SCHEMBL7407234 | 0.82 | F7 (0.48) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL5882097 | 0.80 | F7 (0.46) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL5883068 | 0.80 | F10 (0.42) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL5882852 | 0.79 | F7 (0.43) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL5882374 | 0.77 | F7 (0.43) | F7PRSS1F10F3PRSS2 | |
| SCHEMBL7419688 | 0.75 | FNTA (0.31) | — | |
| SCHEMBL5882586 | 0.73 | F7 (0.45) | F7PRSS1F10F3PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |