Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883061 | 0.83 | AR (0.34) | EPHX2MEN1MAPTKMT2A | |
| SCHEMBL5882935 | 0.82 | MAPT (0.33) | FNTAFNTBEPHX2MEN1MAPT | |
| SCHEMBL5882217 | 0.81 | MMP2 (0.33) | EPHX2MEN1MAPTKMT2A | |
| SCHEMBL5882401 | 0.79 | THRA (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL5883143 | 0.73 | KMT2A (0.36) | MEN1MAPTKMT2A | |
| SCHEMBL5882851 | 0.73 | KMT2A (0.35) | MEN1MAPTKMT2A | |
| SCHEMBL5883108 | 0.69 | PTGDR2 (0.37) | MEN1MAPTKMT2A | |
| SCHEMBL5883227 | 0.68 | F7 (0.46) | — | |
| SCHEMBL5882852 | 0.67 | F7 (0.43) | — | |
| SCHEMBL5884044 | 0.66 | F7 (0.32) | FNTAFNTBEPHX2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |