Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593424 | 0.90 | POLB (0.54) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL28591274 | 0.87 | POLB (0.51) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL12230387 | 0.85 | NPC1 (0.60) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL1734180 | 0.85 | NPC1 (0.60) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL13956980 | 0.84 | NPC1 (0.61) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL2525285 | 0.83 | NPC1 (0.77) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL2389717 | 0.83 | NPC1 (0.77) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL18591288 | 0.83 | LMNA (0.61) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL29841015 | 0.83 | LMNA (0.61) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL28714099 | 0.83 | LMNA (0.61) | NPC1MEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106670-A2 | N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2007-09-20 | — | — | WO | disclosed |
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |