Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094824 | 0.92 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL7411741 | 0.84 | KMT2A (0.53) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL7409439 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL7408157 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL2036338 | 0.81 | KMT2A (0.54) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL4693404 | 0.79 | MAPT (0.59) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL7410135 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL25424836 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| Malonic Acid Diethyl Ester SCHEMBL9840328 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL17430618 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732898-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-03-22 | — | — | US | disclosed |