Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 7/20 | 0.33 |
| ▸ | PLG | P00747 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411988 | 0.88 | F10 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7407496 | 0.86 | F10 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7408430 | 0.85 | F10 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7408558 | 0.85 | F10 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7411701 | 0.85 | F10 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7408226 | 0.85 | F10 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7413908 | 0.84 | F10 (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7414357 | 0.83 | F10 (0.50) | F10PLGPRSS1F2PROC | |
| SCHEMBL7414194 | 0.82 | CACNA1S (0.31) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7115263 | 0.81 | F10 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068191-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999050257-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |