Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.66 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | TLR4 | O00206 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | MLNR | O43193 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570569 | 0.92 | ADRB2 (0.78) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7410044 | 0.87 | ADRB2 (0.67) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7416751 | 0.85 | ADRB2 (0.56) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7410183 | 0.84 | ADRB2 (0.61) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7403484 | 0.84 | ADRB2 (0.63) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7410118 | 0.84 | ADRB2 (0.63) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7411219 | 0.84 | ADRB2 (0.66) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7411563 | 0.83 | ADRB2 (0.60) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL16549983 | 0.83 | ADRB2 (0.62) | ADRB2DRD2MAPTTLR4HTR1A | |
| SCHEMBL7410154 | 0.83 | ADRB2 (0.61) | ADRB2DRD2MAPTTLR4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503067-A | HYPOTENSIVE, ANGINA PECTORIS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-05 | — | — | US | disclosed |