Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452364 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HPGDHDAC1SCD5PPARG | |
| SCHEMBL7408391 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HPGDHDAC1SCD5PPARG | |
| SCHEMBL7412352 | 0.71 | ALDH1A1 (0.34) | ALDH1A1HPGDABCB1HDAC1SCD5 | |
| SCHEMBL7609889 | 0.71 | ALDH1A1 (0.34) | ALDH1A1HPGDABCB1HDAC1SCD5 | |
| SCHEMBL7407274 | 0.71 | HSD17B2 (0.34) | ALDH1A1HPGDSCD5ABHD6DAGLA | |
| SCHEMBL7407270 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HPGDABCB1SCD5PPARG | |
| SCHEMBL7407269 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HPGDABCB1SCD5PPARG | |
| SCHEMBL7604096 | 0.70 | ALDH1A1 (0.36) | ALDH1A1HPGDABCB1HDAC1SCD5 | |
| SCHEMBL7604100 | 0.70 | ALDH1A1 (0.36) | ALDH1A1HPGDABCB1HDAC1SCD5 | |
| SCHEMBL7895764 | 0.67 | KLK7 (0.33) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937042-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998017643-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1998-04-30 | — | — | WO | disclosed |