Efegatran

Efegatran

SCHEMBL7412481

CN[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCNC(=N)N.O=S(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.56
PLG P00747 1/20 0.56
PRSS1 P07477 1/20 0.48
XIAP P98170 5/20 0.47
OPRM1 P35372 6/20 0.46
OPRK1 P41145 6/20 0.46
EPHA2 P29317 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Efegatran SCHEMBL635674 0.97 F2 (0.58) F2PLGPRSS1XIAPOPRM1
Efegatran SCHEMBL7264662 0.94 F2 (0.56) F2PLGPRSS1XIAPOPRM1
Efegatran SCHEMBL7273879 0.94 F2 (0.56) F2PLGPRSS1XIAPOPRM1
Efegatran SCHEMBL564291 0.94 F2 (0.56) F2PLGPRSS1XIAPOPRM1
Efegatran SCHEMBL1229047 0.93 F2 (0.55) F2PLGPRSS1XIAPOPRM1
Hydrochloric Acid SCHEMBL7296655 0.91 F2 (0.59) F2PLGPRSS1XIAPOPRM1
Hydrochloric Acid SCHEMBL7409436 0.91 F2 (0.59) F2PLGPRSS1XIAPOPRM1
SCHEMBL7448422 0.90 F2 (0.58) F2PLGPRSS1
Hydrochloric Acid SCHEMBL7415882 0.89 F2 (0.57) F2PLGPRSS1XIAPOPRM1
Hydrochloric Acid SCHEMBL7413332 0.89 F2 (0.56) F2PLGPRSS1XIAPOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5436229-A Di- and tripeptides as anticoagulants ELI LILLY AND COMPANY (US) 1995-07-25 US claimed