Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7410309 | 0.98 | CYP11B2 (0.41) | CYP11B2HDAC6RPS6KB1 | |
| Hydrochloric Acid SCHEMBL7409759 | 0.97 | CYP11B2 (0.41) | CYP11B2HDAC6RPS6KB1 | |
| SCHEMBL7403889 | 0.91 | SLC6A2 (0.41) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL7414588 | 0.89 | SLC6A2 (0.40) | CYP11B2 | |
| SCHEMBL7415107 | 0.89 | AKT1 (0.41) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL7404571 | 0.86 | MCHR1 (0.40) | CYP11B2 | |
| SCHEMBL7414296 | 0.86 | SLC6A2 (0.53) | — | |
| SCHEMBL7418572 | 0.86 | SLC6A2 (0.50) | — | |
| SCHEMBL7413219 | 0.82 | SLC6A2 (0.35) | — | |
| SCHEMBL7417922 | 0.77 | RPS6KB1 (0.43) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |