Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.62 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412654 | 1.00 | MME (0.62) | MMEECE1AGTR2ACP3FFAR1 | |
| Hydrochloric Acid SCHEMBL7413814 | 0.85 | MME (0.51) | MMEECE1AGTR2ACP3ACE | |
| Hydrochloric Acid SCHEMBL7413822 | 0.85 | MME (0.51) | MMEECE1AGTR2ACP3ACE | |
| SCHEMBL7411689 | 0.85 | MME (0.57) | MMEFFAR1ACEMMEL1 | |
| SCHEMBL7407913 | 0.84 | MME (0.56) | MMEFFAR1ACEMMEL1 | |
| SCHEMBL7411695 | 0.80 | MME (0.60) | MMEFFAR1ACEMMEL1 | |
| SCHEMBL7411683 | 0.80 | MME (0.60) | MMEFFAR1ACEMMEL1 | |
| SCHEMBL7411127 | 0.79 | MME (0.62) | MMEECE1AGTR2ACP3ACE | |
| SCHEMBL7411123 | 0.79 | MME (0.62) | MMEECE1AGTR2ACP3ACE | |
| SCHEMBL489232 | 0.79 | MMEL1 (0.64) | MMEECE1ACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |