Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | ITK | Q08881 | 10/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | NEK4 | P51957 | 1/20 | 0.32 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417175 | 0.89 | F2 (0.36) | F2F10PLGITKAURKA | |
| SCHEMBL7412693 | 0.84 | F2 (0.48) | F2F10PLGKDM4ESMN1; SMN2 | |
| SCHEMBL7415299 | 0.82 | F2 (0.41) | F2F10PLGITKAURKA | |
| SCHEMBL7096731 | 0.81 | F2 (0.37) | F2F10PLGITKALDH1A1 | |
| SCHEMBL7101549 | 0.81 | F2 (0.38) | F2F10PLGITKALDH1A1 | |
| SCHEMBL7413176 | 0.80 | F2 (0.40) | F2F10PLGITKAURKA | |
| SCHEMBL7096708 | 0.79 | F2 (0.40) | F2F10PLGITKAURKA | |
| SCHEMBL7414747 | 0.79 | F2 (0.37) | F2F10PLGITKAURKA | |
| SCHEMBL7413417 | 0.78 | F2 (0.41) | F2F10PLGALDH1A1GAA | |
| SCHEMBL7418083 | 0.78 | F2 (0.41) | F2F10PLGALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |