Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451686 | 0.90 | F2 (0.51) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL7412684 | 0.84 | F2 (0.35) | F2F10LMNASMN1; SMN2KDM4E | |
| SCHEMBL7415304 | 0.82 | F2 (0.59) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL4451687 | 0.81 | F2 (0.64) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL4451691 | 0.81 | F2 (0.64) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL7414753 | 0.81 | F2 (0.49) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL7096732 | 0.81 | F2 (0.52) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL7414751 | 0.81 | F2 (0.48) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL4442315 | 0.81 | F2 (0.59) | F2F10NPC1RAB9APRSS1 | |
| SCHEMBL4442309 | 0.81 | F2 (0.59) | F2F10NPC1RAB9APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |