⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987303 | 0.68 | — | — | |
| SCHEMBL1863689 | 0.68 | — | — | |
| SCHEMBL4754800 | 0.64 | — | — | |
| SCHEMBL8697783 | 0.54 | — | — | |
| SCHEMBL27805069 | 0.53 | — | — | |
| SCHEMBL28326804 | 0.53 | — | — | |
| SCHEMBL7995522 | 0.51 | — | — | |
| Hydrochloric Acid SCHEMBL6509763 | 0.50 | — | — | |
| SCHEMBL3078599 | 0.49 | — | — | |
| SCHEMBL234916 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462696-B1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMA CORP (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0462696-A1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-12-27 | — | — | EP | claimed |
| JP-4225986-A | — | — | None | — | — | JP | disclosed |
| EP-0462696-B1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMA CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| JP-H04225986-A | NOVEL PYRIDO(2,3-F)(1,4)THIAZEPINE AND PYRIDO(3,2-B)(1,5)BENZOTHIAZEPINE | ORTHO PHARMACEUT CORP | 1992-08-14 | — | — | JP | disclosed |
| EP-0462696-A1 | Novel pyrido [2,3-f][1,4] thiazepines and pyrido [3,2-b][1,5] benzothiazepines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-12-27 | — | — | EP | disclosed |
| US-5075440-A | Hypotensive, bronchodilator agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |