Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372849 | 1.00 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1ALDH1A1METAP2 | |
| SCHEMBL7382436 | 0.98 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1ALDH1A1METAP2 | |
| SCHEMBL7372843 | 0.98 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1ALDH1A1METAP2 | |
| SCHEMBL7383092 | 0.87 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7414748 | 0.85 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28912922 | 0.77 | TSHR (0.38) | ALDH1A1OPRD1THRBATML3MBTL1 | |
| SCHEMBL7381461 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLB | |
| SCHEMBL17352429 | 0.73 | TSHR (0.35) | ALDH1A1OPRD1POLB | |
| SCHEMBL7374132 | 0.72 | DPP4 (0.33) | SLC1A3SLC1A2SLC1A1OPRD1KDM4E | |
| SCHEMBL6244065 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922054-B1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2002-08-14 | — | — | EP | disclosed |
| US-6235707-B1 | Anticoagulant peptidyl-arginine aldehyde derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-05-22 | — | — | US | disclosed |
| EP-0922054-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046576-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |