Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.44 |
| ▸ | HTR7 | P34969 | 14/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403937 | 0.89 | HTR1A (0.58) | HTR1AHTR7HTR6CHRM3CHRM2 | |
| SCHEMBL7410972 | 0.85 | TRPV1 (0.38) | — | |
| SCHEMBL7408892 | 0.82 | CHRM3 (0.43) | HTR1AHTR7CHRM3CHRM2CHRM1 | |
| SCHEMBL7409946 | 0.81 | HTR1A (0.61) | HTR1AHTR7HTR6 | |
| SCHEMBL7407854 | 0.79 | CHRM3 (0.44) | HTR1AHTR7CHRM3CHRM2CHRM1 | |
| SCHEMBL7412980 | 0.79 | NISCH (0.48) | HTR1AHTR7HTR6CHRM3CHRM2 | |
| SCHEMBL7413545 | 0.79 | HTR1A (0.47) | HTR1AHTR7HTR6CHRM3CHRM2 | |
| SCHEMBL7413012 | 0.79 | TAAR1 (0.50) | HTR1AHTR7HTR6CHRM3CHRM2 | |
| SCHEMBL7402627 | 0.79 | CHRM3 (0.56) | HTR1AHTR7CHRM3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7408528 | 0.78 | HTR1A (0.46) | HTR1AHTR7HTR6CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |