Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9638087 | 0.94 | OPRM1 (0.53) | OPRM1OPRD1OPRK1KDM4ESLC22A1 | |
| Hydrochloric Acid SCHEMBL8320648 | 0.92 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KDM4ESLC22A1 | |
| Hydrochloric Acid SCHEMBL8318722 | 0.76 | OPRM1 (0.48) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL8320764 | 0.75 | SLC22A1 (0.50) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL29204727 | 0.74 | SLC22A1 (0.54) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Metethoheptazine SCHEMBL2107884 | 0.74 | OPRM1 (0.55) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL10831085 | 0.73 | HTR2C (0.61) | OPRM1OPRD1OPRK1 | |
| SCHEMBL4813929 | 0.73 | SLC22A1 (0.50) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL10831101 | 0.72 | HTR2C (0.60) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL10830523 | 0.72 | HTR2C (0.60) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223530-A | Selective high-affinity ligands for treatment of psychological disorders, side effect reduction | SRI, INTERNATIONAL (US) | 1993-06-29 | — | — | US | claimed |