Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2467399 | 1.00 | — | — | |
| SCHEMBL27981 | 0.94 | — | — | |
| SCHEMBL320609 | 0.94 | MEN1 (1.00) | MEN1MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL3966459 | 0.89 | — | — | |
| Iodide SCHEMBL19178925 | 0.89 | MEN1 (0.89) | MEN1MAPTKMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3672319 | 0.89 | MEN1 (0.89) | MEN1MAPTKMT2ACYP3A4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8051550 | 0.89 | — | — | |
| Fluoride SCHEMBL20497199 | 0.89 | MEN1 (0.89) | MEN1MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL21749649 | 0.89 | — | — | |
| SCHEMBL6010369 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507185-B | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116507185-A | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116507185-B | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116507185-B | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116507185-A | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116507185-A | Formamidine perovskite solar cell and preparation method thereof | 长江三峡集团实业发展(北京)有限公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |