Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.57 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.47 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.89 |
| ▸ | MAPT | P10636 | 2/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL378591 | 1.00 | MEN1 (0.89) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL135990 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4949584 | 1.00 | MEN1 (0.89) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL28945243 | 0.95 | MEN1 (0.80) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL21523285 | 0.95 | MEN1 (0.80) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL10638088 | 0.95 | MEN1 (0.80) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL7371349 | 0.95 | MEN1 (0.80) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| SCHEMBL27981 | 0.94 | — | — | |
| SCHEMBL320609 | 0.94 | MEN1 (1.00) | MEN1MAPTKMT2ACYP3A4TDP1 | |
| Methylamine SCHEMBL27939730 | 0.91 | MAPT (0.73) | MEN1MAPTKMT2ACYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011311-A | Preparation method of metal nanocluster confined covalent organic framework composite material | 西北工业大学 | 2026-05-12 | — | — | CN | disclosed |
| CN-119060606-A | Radiation-resistant color development paint and preparation method and application thereof | 海洋化工研究院有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-118978653-A | Metal nanoparticle domain-limited porous organic framework composite material and preparation method thereof | 西北工业大学 | 2024-11-19 | — | — | CN | disclosed |
| CN-103703056-B | Aramid copolymers | 纳幕尔杜邦公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-2010121714-A1 | COMPLEXES BETWEEN PHOSPHOLIPIDS AND PROTEIN VIMENTIN, AND IN VITRO METHODS FOR THE DETECTION OF ANTIBODIES AGAINST THESE COMPLEXES | DIAMETRA S.R.L. (IT) | 2010-10-28 | — | — | WO | disclosed |
| EP-1766008-A1 | PHAGE SCREENING ASSAY | Moredun Research Institute (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005943-A1 | PHAGE SCREENING ASSAY | MOREDUN RESEARCH INSTITUTE (GB) | 2006-01-19 | — | — | WO | disclosed |
| US-6537546-B2 | Process for macromolecularizing phenolic compounds etc. and use thereof | SDS BIOTECH K.K. (JP) | 2003-03-25 | — | — | US | disclosed |
| US-20010007762-A1 | Process for macromolecularizing phenolic compounds etc. and use thereof | ECHIGO TAKASHI (JP) | 2001-07-12 | — | — | US | disclosed |
| US-6190891-B1 | Process for producing high-molecular-weight phenolic compounds with myrothecium | SHOWA DENKO K.K. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0919628-A1 | PROCESS FOR PRODUCING HIGH-MOLECULAR-WEIGHT COMPOUNDS OF PHENOLIC COMPOUNDS, ETC. AND USE THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-06-02 | — | — | EP | disclosed |