Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA5A | P35218 | 6/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414859 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7416012 | 0.87 | CA1 (0.52) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7411282 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7420995 | 0.86 | CA1 (0.51) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7419003 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7414910 | 0.86 | CA1 (0.49) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7413360 | 0.85 | CA1 (0.49) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7411847 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7413879 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL7416192 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CA1CA2CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |