Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413729 | 1.00 | HTR2C (0.55) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7419732 | 1.00 | HTR2C (0.55) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7413248 | 0.79 | TUBB4A (0.50) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7411406 | 0.79 | TUBB4A (0.50) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7414018 | 0.79 | TUBB4A (0.50) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7411407 | 0.79 | TUBB4A (0.50) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7411786 | 0.75 | SLC6A4 (0.47) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7413066 | 0.75 | SLC6A4 (0.47) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7420516 | 0.75 | SLC6A4 (0.47) | HTR2CSLC6A4TUBB4ATUBBTUBA3C | |
| SCHEMBL7411787 | 0.75 | SLC6A4 (0.47) | HTR2CSLC6A4TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202486-A | Tetrahydroethanonaphthaleneamine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | claimed |
| US-5276026-A | Tetrahydroethanonaphthaleneamine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5202486-A | Tetrahydroethanonaphthaleneamine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | disclosed |