Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 18/20 | 0.78 |
| ▸ | CYP11B1 | P15538 | 17/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004402 | 0.88 | CYP11B2 (1.00) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12302844 | 0.82 | CYP11B1 (0.65) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2150931 | 0.82 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5702666 | 0.81 | CYP1A1 (0.74) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17969382 | 0.80 | CYP11B1 (0.68) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21960161 | 0.80 | CYP11B1 (0.73) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16805040 | 0.79 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9534391 | 0.78 | CYP1A2 (0.63) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19509721 | 0.78 | CYP11B2 (0.70) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25041887 | 0.77 | CYP1A2 (0.83) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613476-A1 | 3-PYRIDINOL DERIVATIVES AND THEIR USE AS MEDICAMENTS | SMITHKLINE BEECHAM PLC (GB) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010114-A1 | 3-PYRIDINOL DERIVATIVES AND THEIR USE AS MEDICAMENTS | SMITHKLINE BEECHAM PLC (GB) | 1993-05-27 | — | — | WO | disclosed |