Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tridecanoate SCHEMBL10007182 | 0.98 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL9387065 | 0.98 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL1982539 | 0.97 | GPR84 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL11045296 | 0.94 | AKR1B1 (0.50) | AKR1B1GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL30231127 | 0.94 | GPR84 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| Undecanoate SCHEMBL28132949 | 0.92 | GPR84 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Myristic Acid SCHEMBL782903 | 0.92 | GPR84 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL28646037 | 0.92 | GPR84 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Oleic Acid SCHEMBL27528473 | 0.90 | PPARG (0.62) | PPARGPPARDPPARATSHRPTPN1 | |
| Oleic Acid SCHEMBL11134816 | 0.89 | PPARG (0.60) | PPARGPPARDPPARATSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721366-A | PHENYLAMIDINE DERIVATIVES | G. D. SEARLE & CO (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |