Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860545 | 1.00 | MAPK1 (0.37) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL741406 | 1.00 | MAPK1 (0.37) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL16005 | 0.85 | MAPK1 (0.35) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL175503 | 0.85 | MAPK1 (0.35) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL28167123 | 0.83 | MAPK1 (0.33) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL11870982 | 0.82 | MAPK1 (0.33) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL28910883 | 0.81 | MAPK1 (0.34) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL11868533 | 0.81 | CPT2 (0.33) | — | |
| SCHEMBL9657732 | 0.81 | CPT2 (0.33) | — | |
| SCHEMBL11868031 | 0.81 | CPT2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |