Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | F3 | P13726 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882047 | 0.75 | F7 (0.69) | F7F10F2PRSS1F3 | |
| SCHEMBL17902821 | 0.73 | SMPD1 (0.54) | KMT2ASMN1; SMN2GPR132MAOBNR4A2 | |
| SCHEMBL19639256 | 0.73 | SMPD1 (0.54) | KMT2ASMN1; SMN2GPR132MAOBNR4A2 | |
| Trifluoroacetic Acid SCHEMBL5882279 | 0.73 | F7 (0.62) | F7F10F2PRSS1F3 | |
| SCHEMBL5881929 | 0.72 | SGMS2 (0.58) | F7F10F2PRSS1F3 | |
| SCHEMBL4599877 | 0.72 | F10 (0.48) | F7F10F2PRSS1F3 | |
| SCHEMBL27502186 | 0.72 | SMN1; SMN2 (0.49) | F7F10F2PRSS1F3 | |
| SCHEMBL5883277 | 0.72 | F7 (0.46) | F7F10F2PRSS1F3 | |
| SCHEMBL5883266 | 0.71 | F7 (0.47) | F7F10F2PRSS1F3 | |
| SCHEMBL30771236 | 0.70 | SYK (0.50) | KMT2ASMN1; SMN2GPR132MAOBPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |