Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426935 | 0.89 | CYP1A2 (0.39) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL3497629 | 0.82 | ABCC1 (0.55) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL1098305 | 0.81 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL16817403 | 0.81 | FABP4 (0.53) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL14317217 | 0.80 | MAPT (0.46) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL16817608 | 0.77 | MAPT (0.49) | MEN1KMT2AABCC1ABCG2MAPT | |
| SCHEMBL14645285 | 0.74 | CYP1A2 (0.46) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL25969748 | 0.73 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL23274029 | 0.73 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL23289627 | 0.73 | CNR2 (0.44) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |