Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | MMP13 | P45452 | 6/20 | 0.47 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414550 | 1.00 | HSD17B10 (0.48) | HSD17B10SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL7344292 | 0.89 | SLC1A3 (0.53) | HSD17B10SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL7344297 | 0.89 | SLC1A3 (0.53) | HSD17B10SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL7414842 | 0.84 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL7414840 | 0.84 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL22234176 | 0.84 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL3120047 | 0.84 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL7341150 | 0.84 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL29541878 | 0.83 | SLC1A3 (0.48) | HSD17B10SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL16330779 | 0.81 | HSD17B10 (0.57) | HSD17B10SLC1A3SLC1A2SLC1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |