Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 13/20 | 0.45 |
| ▸ | MMP9 | P14780 | 8/20 | 0.45 |
| ▸ | MMP13 | P45452 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414842 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7344297 | 0.87 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7344292 | 0.87 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7414550 | 0.84 | HSD17B10 (0.48) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7414546 | 0.84 | HSD17B10 (0.48) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7413170 | 0.82 | MMP2 (0.48) | MMP2MMP9MMP13MMP1MMP8 | |
| SCHEMBL7341150 | 0.82 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL22234176 | 0.82 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL3120047 | 0.82 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL29541878 | 0.81 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |