Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419945 | 0.85 | MAOB (0.49) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3800271 | 0.85 | GAA (0.56) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL31074140 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11MAOBSMN1; SMN2NPC1 | |
| SCHEMBL1125421 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11MAOBSMN1; SMN2NPC1 | |
| SCHEMBL1124344 | 0.84 | CYP4Z1 (0.54) | CYP4F2CYP4A11SMN1; SMN2NPC1PKM | |
| SCHEMBL10411098 | 0.84 | MAOB (0.51) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| Methane SCHEMBL10411744 | 0.83 | MAOB (0.50) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1403568 | 0.83 | PTGS1 (0.67) | MAOBSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL13900842 | 0.79 | CYP4F2 (0.56) | CYP4F2CYP4A11MAOBSMN1; SMN2MAPT | |
| SCHEMBL24368273 | 0.79 | MAOB (0.50) | MAOBSMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |