Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823596 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL29181630 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL29605097 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL9935617 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL30462264 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL31482354 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL7414784 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL460837 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL31188758 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL6312855 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391554-B1 | Dopamine receptor ligands and imaging agents | UNIV PENNSYLVANIA (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5130117-A | Imaging agents; monitor effectiveness of drugs in nervous and mental disorders | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1992-07-14 | — | — | US | disclosed |
| US-5068326-A | Agents for imaging human brains, 8-chloro-2,3,4,5-tetrahydro-3 -methyl-5-(4'-(125I)iodophenyl)-1H-3-benzazepine | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1991-11-26 | — | — | US | disclosed |
| EP-0391554-A1 | Dopamine receptor ligands and imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1990-10-10 | — | — | EP | disclosed |