Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415031 | 1.00 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8569330 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8569327 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8569332 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8564381 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8564379 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8564374 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8570067 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8570069 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8568440 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |