Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452481 | 0.96 | F2 (0.39) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7420260 | 0.96 | F2 (0.39) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7419831 | 0.95 | F2 (0.38) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7417541 | 0.95 | F2 (0.39) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7447260 | 0.94 | F2 (0.41) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7416279 | 0.94 | F2 (0.38) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7450699 | 0.94 | F2 (0.38) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7420225 | 0.94 | F2 (0.38) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7418783 | 0.93 | F2 (0.46) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7450016 | 0.93 | ALDH1A1 (0.37) | RAB9AALDH1A1NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |