SCHEMBL7415136

SCHEMBL7415136

CCCCCc1ccccc1CCl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.55
NR1H2 P55055 1/20 0.45
NR1H3 Q13133 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
KCNH2 Q12809 2/20 0.44
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
TLR8 Q9NR97 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
THRA P10827 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780518 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL6705516 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL11871253 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL10608856 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL11466723 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL11870161 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL11870689 0.98 LIPG (0.58) LIPGNR1H2NR1H3ALOX5PTGS2
Ammonia Solution, Strong SCHEMBL1109934 0.96 LIPG (0.56) LIPGNR1H2NR1H3ALOX5PTGS2
Ammonia Solution, Strong SCHEMBL2313869 0.96 LIPG (0.56) LIPGNR1H2NR1H3ALOX5PTGS2
Ammonia Solution, Strong SCHEMBL20657023 0.96 LIPG (0.56) LIPGNR1H2NR1H3ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101107286-A Poly(arylenevinylene) and poly(heteroarylenevinylene) light emitting polymers and polymer light-emitting devices AGENCY SCIENCE TECH & RES (SG) 2008-01-16 CN disclosed
EP-1150957-A1 N-CARBOXYMETHYL SUBSTITUTED BENZOLACTAMS AS INHIBITORS OF MATRIX METALLOPROTEINASE Aventis Pharmaceuticals Inc. (US) 2001-11-07 EP disclosed
WO-2000040564-A1 N-CARBOXYMETHYL SUBSTITUTED BENZOLACTAMS AS INHIBITORS OF MATRIX METALLOPROTEINASE AVENTIS PHARMACEUTICALS INC. (US) 2000-07-13 WO disclosed
EP-0802936-A1 CROSSLINKED SEEDED COPOLYMER BEADS AND PROCESS OF MANUFACTURE THE DOW CHEMICAL COMPANY (US) 1997-10-29 EP disclosed
WO-1996013533-A1 CROSSLINKED SEEDED COPOLYMER BEADS AND PROCESS OF MANUFACTURE THE DOW CHEMICAL COMPANY (US) 1996-05-09 WO disclosed
EP-0182872-A4 A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. DOW CHEMICAL CO (US) 1986-08-21 EP disclosed
EP-0182872-A1 A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. DOW CHEMICAL CO (US) 1986-06-04 EP disclosed
US-4570011-A PYROLYSIS OF AN ORTHO ALKYL HALOMETHYL AROMATIC HYDROCARBON IN AN INERT THE DOW CHEMICAL COMPANY (US) 1986-02-11 US disclosed
WO-1985005355-A1 A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS THE DOW CHEMICAL COMPANY (US) 1985-12-05 WO disclosed
US-3998776-A Isothiouronium stabilized latexes THE DOW CHEMICAL COMPANY (US) 1976-12-21 US disclosed