Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030254 | 0.98 | MEN1 (0.31) | MEN1MAPTKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL29030267 | 0.98 | MEN1 (0.31) | MEN1MAPTKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL28743001 | 0.98 | MEN1 (0.31) | MEN1MAPTKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7771253 | 0.75 | — | — | |
| SCHEMBL20122754 | 0.75 | — | — | |
| SCHEMBL29030080 | 0.73 | — | — | |
| SCHEMBL28629969 | 0.73 | — | — | |
| SCHEMBL1895847 | 0.70 | ALOX5 (0.35) | — | |
| SCHEMBL775803 | 0.70 | — | — | |
| SCHEMBL233054 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579650-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017460-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| US-4182629-A | Photochromic compounds | HELLER HAROLD G (GB) | 1980-01-08 | — | — | US | disclosed |
| US-4145536-A | Photochromic compounds | HELLER HAROLD G | 1979-03-20 | — | — | US | disclosed |