Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 7/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415262 | 0.91 | MME (0.42) | MMEMMEL1 | |
| SCHEMBL7411689 | 0.88 | MME (0.57) | MMEMMEL1 | |
| SCHEMBL7407200 | 0.86 | MME (0.47) | MMEMMEL1 | |
| SCHEMBL7348038 | 0.83 | MME (0.51) | MME | |
| SCHEMBL7318673 | 0.83 | HDAC1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL7413814 | 0.83 | MME (0.51) | MMEMMEL1 | |
| SCHEMBL7322712 | 0.83 | MME (0.51) | MME | |
| Hydrochloric Acid SCHEMBL7413822 | 0.83 | MME (0.51) | MMEMMEL1 | |
| SCHEMBL8921950 | 0.82 | MMEL1 (0.48) | MMEMMEL1 | |
| Hydrochloric Acid SCHEMBL17965428 | 0.79 | MME (0.53) | MMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |