SCHEMBL741560

SCHEMBL741560

O=C(CC(=O)OCCCCCO)OCCCCCO

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.50
FAAH O00519 2/20 0.47
NAAA Q02083 1/20 0.46
GAA P10253 2/20 0.44
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
EPHX1 P07099 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21143381 1.00 ACHE (0.50) ACHEFAAHNAAAGAAMGAM
SCHEMBL6681823 1.00 ACHE (0.50) ACHEFAAHNAAAGAAMGAM
SCHEMBL6680478 1.00 ACHE (0.50) ACHEFAAHNAAAGAAMGAM
SCHEMBL822176 0.97 ACHE (0.47) ACHEFAAHNAAAGAAMGAM
SCHEMBL6681554 0.90 GAA (0.43) ACHEFAAHNAAAGAAMGAM
SCHEMBL741589 0.89 ACHE (0.47) ACHEFAAHNAAAGAAMGAM
SCHEMBL743412 0.89 ACHE (0.47) ACHEFAAHNAAAGAAMGAM
SCHEMBL6680472 0.89 ACHE (0.46) ACHEFAAHNAAAGAARAD52
SCHEMBL6681819 0.89 ACHE (0.46) ACHEFAAHNAAAGAARAD52
SCHEMBL10910388 0.89 ACHE (0.46) ACHEFAAHNAAAGAARAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103626651-B Method for preparing vinpocetine intermediate gamma-hydroxypropyl-ethylmalonic acid NORTHEAST PHARMACEUTICAL GROUP CO LTD 2015-07-22 CN claimed
US-10884348-B2 Electrophotographic photoreceptor, and electrophotographic cartridge and image forming apparatus including same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-20190219938-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC CARTRIDGE AND IMAGE FORMING APPARATUS INCLUDING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-18 US disclosed
CN-109791381-A Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same 三菱化学株式会社 2019-05-21 CN disclosed
US-20170349702-A1 POLYESTER MACROMERS CONTAINING 1,1-DICARBONYL-SUBSTITUTED 1 ALKENES NIPPON SHOKUBAI CO., LTD. (JP) 2017-12-07 US disclosed
US-20170349702-A1 POLYESTER MACROMERS CONTAINING 1,1-DICARBONYL-SUBSTITUTED 1 ALKENES NIPPON SHOKUBAI CO., LTD. (JP) 2017-12-07 US disclosed
US-20170349781-A1 COATINGS CONTAINING POLYESTER MACROMERS CONTAINING 1,1-DICARBONYL-SUBSTITUTED 1 ALKENES SIRRUS, INC. 2017-12-07 US disclosed
US-20170349781-A1 COATINGS CONTAINING POLYESTER MACROMERS CONTAINING 1,1-DICARBONYL-SUBSTITUTED 1 ALKENES SIRRUS, INC. 2017-12-07 US disclosed
US-9745413-B1 Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes SIRRUS, INC. (US) 2017-08-29 US disclosed
US-9745413-B1 Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes SIRRUS, INC. (US) 2017-08-29 US disclosed
US-9718989-B1 Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes SIRRUS, INC. (US) 2017-08-01 US disclosed
US-9617377-B1 Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes NIPPON SHOKUBAI CO., LTD. (JP) 2017-04-11 US disclosed
US-9617377-B1 Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes NIPPON SHOKUBAI CO., LTD. (JP) 2017-04-11 US disclosed
US-9567475-B1 Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes SIRRUS, INC. (US) 2017-02-14 US disclosed
US-9567475-B1 Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes SIRRUS, INC. (US) 2017-02-14 US disclosed
CN-103626651-B Method for preparing vinpocetine intermediate gamma-hydroxypropyl-ethylmalonic acid NORTHEAST PHARMACEUTICAL GROUP CO LTD 2015-07-22 CN disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349702-A1 POLYESTER MACROMERS CONTAINING 1,1-DICARBONYL-SUBSTITUTED 1 ALKENES DCLRE1A, MCCC2, DDR1 ACHE 1947/4885FAAH 2536/4885NAAA 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.