Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | NOS2 | P35228 | 3/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL7415976 | 1.00 | NOS3 (0.53) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL29400795 | 0.90 | SLC7A5 (0.65) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL14935980 | 0.90 | SLC7A5 (0.65) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL44026 | 0.90 | SLC7A5 (0.65) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL29567654 | 0.90 | SLC7A5 (0.65) | NOS3NOS1NOS2SLC7A5ALPI | |
| SCHEMBL44027 | 0.90 | SLC7A5 (0.65) | NOS3NOS1NOS2SLC7A5ALPI | |
| Hydrochloric Acid SCHEMBL20502134 | 0.88 | SLC7A5 (0.62) | NOS3NOS1NOS2SLC7A5ALPI | |
| Hydrochloric Acid SCHEMBL20502133 | 0.88 | SLC7A5 (0.62) | NOS3NOS1NOS2SLC7A5ALPI | |
| Hydrochloric Acid SCHEMBL22264913 | 0.88 | SLC7A5 (0.62) | NOS3NOS1NOS2SLC7A5ALPI | |
| Hydrochloric Acid SCHEMBL31320951 | 0.88 | SLC7A5 (0.62) | NOS3NOS1NOS2SLC7A5ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084137-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2001-03-21 | — | — | EP | claimed |
| WO-1999064442-A1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI S.P.A. (IT) | 1999-12-16 | — | — | WO | claimed |