Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419739 | 0.94 | ITGB3 (0.38) | ITGB3ITGA2BHTT | |
| SCHEMBL7419044 | 0.89 | ITGB3 (0.34) | ITGB3ITGA2BHTT | |
| SCHEMBL7414406 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BHTT | |
| SCHEMBL8117264 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BHTT | |
| SCHEMBL7418297 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BHTT | |
| SCHEMBL7419412 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7422459 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BHTT | |
| SCHEMBL7416273 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7416268 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7416280 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |
| JP-3034046-B2 | — | — | 2000-04-17 | — | — | JP | claimed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |