Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425175 | 0.86 | TSHR (0.48) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL11355081 | 0.85 | — | — | |
| SCHEMBL7422695 | 0.81 | TSHR (0.41) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL188204 | 0.79 | — | — | |
| SCHEMBL722046 | 0.78 | TSHR (0.42) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2949576 | 0.76 | MEN1 (0.41) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL31307045 | 0.76 | — | — | |
| SCHEMBL7416335 | 0.76 | — | — | |
| SCHEMBL2964622 | 0.76 | MEN1 (0.41) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL723665 | 0.76 | HTT (0.41) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0413544-B1 | Purine derivatives, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1997-01-02 | — | — | EP | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |
| US-5252575-A | Herpes virus | BEECHAM GROUP P.L.C. (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0413544-A2 | Purine derivatives, process for their preparation, pharmaceutical compositions and intermediates | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |