Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355081 | 0.91 | — | — | |
| SCHEMBL7416338 | 0.86 | TSHR (0.36) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL25841034 | 0.86 | TSHR (0.52) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL546849 | 0.78 | MEN1 (0.54) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL7422695 | 0.77 | TSHR (0.41) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL31307045 | 0.77 | — | — | |
| Butoxyethanol SCHEMBL8584938 | 0.77 | TSHR (0.71) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL9640229 | 0.77 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL9639247 | 0.77 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL3876514 | 0.77 | MEN1 (0.58) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |