Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.50 |
| ▸ | FNTB | P49356 | 11/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420603 | 0.92 | KCNH2 (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7420645 | 0.86 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7424679 | 0.86 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7423027 | 0.84 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7421298 | 0.84 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7428975 | 0.84 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7419872 | 0.83 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7416481 | 0.83 | BRD4 (0.45) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7420186 | 0.82 | FNTA (0.55) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7417103 | 0.82 | FNTA (0.57) | FNTAFNTBPGGT1BKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |