Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419390 | 0.83 | CHRM3 (0.54) | HTR4CHRM3 | |
| SCHEMBL7414220 | 0.83 | CCR3 (0.64) | CCR3HTR4HTT | |
| SCHEMBL21059235 | 0.79 | KMT2A (0.61) | HTT | |
| SCHEMBL21059249 | 0.78 | KMT2A (0.60) | HTT | |
| SCHEMBL5221853 | 0.78 | MAPK1 (0.46) | CCR3CHRM3HTT | |
| SCHEMBL6581593 | 0.77 | BCHE (0.47) | CCR3CHRM3HTT | |
| SCHEMBL21059226 | 0.77 | KMT2A (0.58) | HTT | |
| SCHEMBL21059154 | 0.77 | KMT2A (0.67) | HTT | |
| SCHEMBL17207034 | 0.76 | CHRM3 (0.52) | CHRM3 | |
| SCHEMBL6421183 | 0.76 | CHRM3 (0.53) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629198-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993018027-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-16 | — | — | WO | disclosed |