SCHEMBL7416583 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	5/20	0.47

▸	NPY4R	P50391	9/20	0.46

▸	NPY1R	P25929	6/20	0.46

▸	ANPEP	P15144	1/20	0.43

▸	RNPEP	Q9H4A4	1/20	0.43

▸	DNPEP	Q9ULA0	1/20	0.43

▸	NPY2R	P49146	4/20	0.43

▸	NPY5R	Q15761	4/20	0.43

▸	DPP8	Q6V1X1	1/20	0.40

▸	DPP7	Q9UHL4	1/20	0.40

▸	ALPI	P09923	1/20	0.40

▸	PKM	P14618	1/20	0.40

▸	PTGS1	P23219	1/20	0.40

▸	XIAP	P98170	1/20	0.40

▸	SLC7A5	Q01650	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phenylalanine SCHEMBL17962430	0.90	SLC7A5 (0.50)	MMP2NPY4RNPY1RANPEPRNPEP
SCHEMBL1537375	0.86	ANPEP (0.47)	MMP2NPY4RNPY1RANPEPRNPEP
SCHEMBL1401439	0.86	ANPEP (0.47)	MMP2NPY4RNPY1RANPEPRNPEP
SCHEMBL3362561	0.86	DPP8 (0.50)	NPY4RNPY1RANPEPDPP8DPP7
SCHEMBL22133069	0.86	DPP8 (0.50)	NPY4RNPY1RANPEPDPP8DPP7
SCHEMBL7758995	0.86	DPP8 (0.50)	NPY4RNPY1RANPEPDPP8DPP7
Hydrochloric Acid SCHEMBL27766761	0.85	DPP8 (0.49)	NPY4RNPY1RANPEPDPP8DPP7
Hydrochloric Acid SCHEMBL27766760	0.85	DPP8 (0.49)	NPY4RNPY1RANPEPDPP8DPP7
Dl-Phenylalanine SCHEMBL27756967	0.84	SLC7A5 (0.49)	NPY4RNPY1RANPEPRNPEPDNPEP
SCHEMBL21722100	0.83	LMNA (0.52)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1990014362-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1990-11-29	—	—	WO	disclosed